July 09, 2020 9 min read
Something is just not right with your beloved pet. You dread the appointment you just made with your veterinarian and you pray that the news you hear will not include the big “C” word — Cancer.
These days, it seems most pets are being diagnosed with some sort of cancer, whether it be a rare or common form. But, does cancer have to result in euthanizing a beloved pet? Absolutely not! Ozone therapy is a little known treatment that can help your pet’s body attack cancer cells and restore his/her health.
STUDY | TREATMENT, APPLICATION ROUTE AND DOSAGE |
RESULTS | REFERENCES |
Murine Tumors: Ehrlich's Ascites (TAE), Lung Tumor RL-67, L1210 Leukemia and L-P388 Leukemia |
Rectal and intratumoral routes (6, 12 and 49 mg/L) | Tumors were not reduced. Only lung metastasis decreased | Rodriguez et al., 1998 |
Mice with TAE and Sarcoma-37 | Rectal route, OOP (19, 26 and 42 mg/L) 1 ml per animal, 12 days | Reduced the number of disseminated cells in the lung, dependent dose | Menendez et al., 2008 |
Lewis Lung Carcinoma (Mice) | OOP 4, 11, 20 and 35 mg/L, i.p route, 15 applications |
Significantly reduced tumor size of Lewis Lung carcinoma cells | Menendez et al., 2008 |
Rabbits, VX2 Tumor, Head and Neck | OOP (50 mg/ml of OOM 80 ml/kg volume of weight) intraperitoneally, during 5 days | 50% survival and 85% had regression of the tumor with no metastasis. Increased leukocytes and prostacyclin | Schultz et al., 2008 Schultz et al., 2012 |
Rabbits, VX2 Tumor, Head and Neck | OOP (50 mg/ml of OOM 80 ml/kg volume of weight) intraperitoneally, during 5 days | Regression of the tumor mass, associated with the increase of the CD3 white cells and its infiltration to the tumor tissue and COX-2 | Rossman et al., 2014 |
Proctitis Induced by Irradiation in Rats | Treatment with OOO, rectal 1 ml, during 10 days | Reduced inflammation and histological changes | Gultekin et al., 2013 |
Radiation Damage to Liver, Lung and Intestine in Rats | OOP (60 mg/ml of OOM) vol. 2, 3 ml/ animal, for a 0,7 mg/kg dose intraperitoneally, during 5 days prior to the injury | Reduced FNT, IL1 and AST and ALAT levels. Increased SOD activity and preserved tissue structure | Bakkal et al., 2013 Gultekin et al., 2013 |
Damage to Methotrexate-Induced Ileum, Liver and Kidneys in Rats | OOP at 0,72 mg/kg dose, applied intraperitoneally for 15 days | Increased GSH content in renal tissue and reduced levels of proinflammatory cytokines | Kesik et al., 2009 Aslaner et al., 2015 |
Kidney Damage by Cisplatin in Rats | OOM treatment (10, 30 and 50 mg/L) applied rectally for 5 consecutive days | Attenuated renal histological damage and restored levels of GSH, CAT, SOD and GPx depleted by CDDP | Gonzalez et al., 2004 |
Kidney Damage by Cisplatin in Rats | OOP applied rectally for 15 days in the model of CDDP-induced renal damage. OM at the same doses as the previous one | Protected kidney tissue by restoring the enzymatic antioxidant system (SOD, CAT, GPx) of renal tissue, thus preserving both renal structure and function. Reduced Apoptosis | Borrego et al., 2004 Borrego et al., 2006 |
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